摘要
研究发现成纤维细胞生长因子23与慢性肾脏疾病患者心血管病变的发生、发展和预后显著相关,而且新近的研究发现其与非慢性肾脏疾病患者心血管疾病亦密切相关。现主要通过介绍成纤维细胞生长因子23在非慢性肾脏疾病患者心血管病变中的作用和可能机制,从而评价成纤维细胞生长因子23是否有希望成为新型心血管疾病预后因子。
Fibroblast growth factor 23（FGF23）has been found to be closely related to the occurrence,development and prognosis of cardiovascular disease（CVD）in chronic kidney disease（CKD）.Coincidentally,the recent studies found it also applied to non-CKD patients.This article mainly reviews the relationship between FGF23 and CVD in non-CKD patients and possible mechanisms,to evaluate whether FGF23 is promising to become a new CVD prognostic factor.
作者
张云霄
白瑾
ZHANG Yunxiao 1 ,BAI Jin 1,2(1.Peking University Third Hospital,Beijing 100191,China; 2.Department of Cardiology,Peking University Third Hospital,Beijing 100191,Chin)
出处
《心血管病学进展》
CAS
2018年第5期695-699,共5页
Advances in Cardiovascular Diseases
基金
国家科技支撑计划(2016YFC1301301)
