便通胶囊治疗全子宫切除术后便秘的临床研究

Clinical Effects of Biantong Capsules in Treatment of Panhysterectomy Postoperative Constipation

目的:比较便通胶囊与芪蓉润肠口服液治疗全子宫切除术后患者便秘的疗效与安全性。方法:选取2015年8月至2016年12月首都医科大学附属安贞医院收治的全子宫切除术后患者112例,随机分为观察组和对照组各56例,分别口服便通胶囊与芪蓉润肠口服液。记录2组患者首次排便时间、住院时间,停药后1月、2月及3月便秘的复发率及安全性。结果:对照组有4例患者因治疗72 h无效提前退出试验,观察组首次排便时间较对照组提前了0.48 d(P<0.05),观察组住院时间较对照组缩短了0.22 d(P<0.05),且停药后2月及3月观察组便秘复发率也显著低于对照组(P<0.05)。2组不良反应发生率均较低,并且组间比较无统计学意义。结论:便通胶囊治疗全子宫切除术后便秘患者,起效迅速,显著缩短患者住院时间且复发率低,安全性佳,值得临床推广应用。

Objective： To assess the clinical effects and safety of the Biantong Capsules and Qirong Runchang Oral Liquid in the treatment of panhysterectomy postoperative constipation.Methods： A total of 112 cases who were admitted and received the panhysterectomy were randomly divided into two groups,with 56 cases in each group.The treatment group of patients were treated with Biantong Capsules,while patients in the control group were treated with Qirong Runchang Oral Liquid.First defecation time,length of hospital stay,recurrence and safety of constipation 1 month,2 months and 3 months after drug withdrawal were recorded.Results： 4 patients in the control group terminated the test in advance due to ineffective treatment after 72 hours of treatment.The first defecation time in the treatment group was 0.48 day early than that in the control group（ P〈0.05）; and the hospitalization time of the treatment group was significantly 0.22 day shorter than that of the control group（ P〈0.05）.The recurrence rate of the treatment group was significantly lower than that of the control group 2 months and 3 months after drug withdrawal（ P〈0.05）.The adverse effects rate of the two groups was low and there was no significant difference between the two groups.Conclusion： Biantong Capsules in treatment of panhysterectomy postoperative constipation have rapid effects and good safety,shorten the hospitalization time,reduce the recurrence rate worthy of promotion,which was worthy of clinical promotion.