通腑泄热中药治疗急性胰腺炎的系统评价

Systematic Analysis of Purging Bowels and Expelling Heat Prescription in the Treatment of Acute Pancreatitis

目的:评价通腑泄热中药对治疗急性胰腺炎的疗效,为其应用提供循证医学依据。方法:选取2014年1月至2017年10月通腑泄热法治疗急性胰腺炎的随机对照实验研究,按照Cochrance协作网系统评价员手册对纳入文献进行质量风险评估,使用Revman5.3软件进行数据处理,从符合研究标准的文献进行疗效分析,同时对各种中药的给药途径和使用频率进行分析。结果:共计11项随机对照试验790例急性胰腺炎患者纳入研究(重写结果)。结论:在西医常规治疗的基础上,合并通腑泄热类中药对于治疗急性胰腺炎有较好的临床疗效。但纳入的试验质量普遍较低。

Objective： To evaluate the therapeutic effect of purging bowels and expelling heat prescription for the acute pancreatitis.Methods： The RCT of purging bowels and expelling heat prescription for the acute pancreatitis from January 2014 to October2017 were searched in the databases.According to the Cochrance Collaboration System Evaluator＇s Manual,the quality risk assessment was carried out on the included literature,and Revman5.3 software was used for data processing.The efficacy analysis was carried out from the literature meeting the research criteria,and the route of administration and frequency of use of various Chinese medicines were analyzed.Results： 11 RCTs and 790 patients with acute pancreatitis were included.Conclusion： The systematic evaluation analysis showed that on the basis of the conventional treatment of western medicine,the combination of purging bowels and expelling heat prescription has good clinical effects on the treatment of acute pancreatitis.However,the quality of the included trials is generally low,and it is still necessary to evaluate the effectiveness of high-quality large-scale clinical trials in the future.