加强我国胰源性糖尿病的研究

Strengthening the research of pancreatogenic diabetes

胰源性糖尿病是指由于胰腺外分泌功能异常导致的糖尿病,属继发性糖尿病的一种,1999年WHO糖尿病分类中把它归类为3C型糖尿病(T3c DM).既往认为T3c DM患病率较低,占糖尿病人群的0.50%~1.15%;近年报道,糖尿病人群中其患病率为5%~10%,因此现在认为T3c DM的患病率是被低估的.相对于T1DM和T2DM,我国对于T3c DM认识明显不足,主要表现为对T3c DM的发病机制研究不充分、没有详细的流行病学资料、缺乏有效的胰腺外分泌功能评估方法和筛查路径、缺乏该类疾病干预治疗的循证医学证据及相应的治疗指南.本文将从T3c DM的流行病学现状,临床特点及诊断和治疗进行综述,希望引起国内同行对T3c DM的关注,加强对T3c DM的研究和诊治.

Type 3 c diabetes mellitus（T3 c DM） is a diabetes mellitus secondary to pancreatic diseases. It is previously believed that the prevalence of this disease was low, accounting for 0.5%–1.15% of the diabetes population. Recent data on type 3 c diabetes（T3 c DM）showed that it might be more common than reported previously. It is 5%–10% among all diabetic subjects in Western populations. Its prevalence and clinical importance have been underestimated and underappreciated. In contrast to the management of type 1 or type 2 diabetes, the pathogenesis of T3 c DM is very complex and complicated. The failure to correctly diagnose T3 c DM may lead to failure to implement an appropriate medical therapy on these patients. The purpose of this review is to draw attention to T3 c DM and to strengthen research and diagnosis of this disease.