针刀联合消瘀散外敷治疗膝骨关节炎的临床观察

Clinical observation on acupotomy combined with external application of Xiaoyu Powder in treating knee osteoarthritis

目的观察针刀联合消瘀散外敷治疗膝骨关节炎的临床疗效。方法将111例膝骨关节炎患者随机分为治疗组(55例)与对照组(56例)。治疗组予针刀联合消瘀散外敷,对照组予扶他林乳胶剂外涂。两组疗程均为2周,比较膝关节功能相关评分(Lysholm评分、WOMAC评分)、膝关节疼痛评分(VAS评分)、膝关节肿胀程度及活动度,观察用药安全性。结果 (1)最终完成试验者,治疗组与对照组各50例。(2)治疗前与治疗后1个月、治疗后3个月分别组内比较,两组Lysholm评分均明显升高(P<0.05),而WOMAC、VAS评分均明显降低(P<0.05)。组间治疗后1个月、治疗后3个月比较,治疗组Lysholm评分均明显高于对照组(P<0.05),而WOMAC、VAS评分均明显低于对照组(P<0.05)。(3)治疗前与治疗后1个月、治疗后3个月分别组内比较,治疗组膝关节肿胀程度明显减轻(P<0.05),而屈曲度明显增加(P<0.05)。组间治疗后1个月、治疗后3个月比较,治疗组膝关节肿胀程度明显轻于对照组(P<0.05),而屈曲度明显大于对照组(P<0.05)。(4)两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论针刀联合消瘀散外敷治疗膝骨关节炎,可明显减轻膝关节疼痛及肿胀,改善其活动度。

Objective To observe the clinical efficacy of acupotomy combined with external application of Xiaoyu Powder in the treatment of knee osteoarthritis.Methods 111 patients with knee osteoarthritis were randomly divided into the treatment group（55 cases） and control group（56 cases）. The treatment group was treated with acupotomy combined with external application of Xiaoyu Powder,the control group was treated with external application of Votalin emulsion,with a course of 2 weeks. The knee joint function related scores including Lysholm score and WOMAC score,knee joint pain score（VAS score）,knee joint swelling degree and mobility were evaluated. The medication safety was observed. Results（1）Finally 50 cases in the treatment group and 50 cases in the control group completed the trial.（2）Compared with treatment before,the Lysholm score was increased in both groups one month and three months after treatment（P〈0.05）,while the WOMAC score and VAS score were significantly decreased（P〈0.05）. One month and three months after treatment,the Lysholm score in the treatment group was obviously higher than that in the control group（P〈0.05）,while the WOMAC score and VAS score were significantly lower than those in the control group（P〈0.05）.（3）Compared with treatment before,the knee joint swelling degree in the treatment group was obviously alleviated（P〈0.05）,while the range of flexion was obviously increased（P〈0.05） one month and three months after treatment. One month and three months after treatment,the knee joint swelling degree in the treatment group was obviously slighter than that in the control group（P〈0.05）,while the range of flexion was obviously greater than that in the control group（P〈0.05）.（4）There was no statistically significant difference on incidence rate of adverse reactions between the two groups（P〈0.05）. Conclusion Acupotomy combined with external application of Xiaoyu Powder in the treatment of knee osteoarthritis can obviously alleviate the pain and swelling of knee joint,and improve the mobility.