T_2N_0M_0期低位直肠癌经肛门切除联合放化疗的疗效分析

The clinical analysis of the transanal excision combined with chemoradiation in T_2N_0M_0-low rectal cancer

目的:探讨T_2N_0M_0期低位直肠癌经肛门局部切除联合放化疗的临床适应证及应用价值。方法:回顾性分析2012年1月至2015年1月期间我院收治的22例T_2N_0M_0期低位直肠癌患者,分为经肛门局部切除联合放化疗组(10例)和根治性切除组(12例)。对比两组患者的各种临床病理特征及疗效。结果:两组患者肿瘤大小、肿瘤距肛缘距离比较无统计学差异(P>0.05);术后住院天数、术中出血量、术后并发症发生率及手术时间比较有统计学差异(P<0.05)。结论:分化较好的T_2N_0M_0期低位直肠癌经肛门切除联合放化疗与根治性手术比较治疗效果相当,但手术操作简单,创伤小,恢复快、并发症少、术后生活质量高,具有一定优势,在有适应证患者中可以推广。

Objective ：To investigate the clinical value of the transanal local excision combined with ehemoradi-ation of T2NoM0-low rectal cancer. Methods ：The elinieopathologieal data in 22 eases from Jan. 2012 to Jan. 2015 with low rectal cancer were retrospectively reviewed. The patients were assigned into two groups：10 eases in transanal excision combined with ehemoradiation group and 12 eases in radical excision group. The clinieopathologie features of two groups were compared. Results：There were no significant differences in the tumor size, the tumor distance from a-nal edge between the two groups （ P 〉 0.05 ）. There were significant differences in post-operation hospital stay, blood loss during operation, complication rate and operation time between the two groups （ P 〈 0.05 ）. Conclusion ： The cur-ative effect is the same between radical excision and transanal excision combined with chemoradiation in well differen-tiated T2N0M0-low rectal cancer. The transanal excision combined with chemoradiation is more easy and has less trauma, rapid recovery, less complication, high life quality after operation.