喷膜剂的研究进展

Advances in film-forming spray

喷膜剂是一种结合喷雾剂和膜剂优点的外用给药新剂型,可用于抗菌、镇痛、精神和激素类药物的局部给药,尤其适合创面防护类药物,具有定量输出、给药便捷、顺应性好、提高药物生物利用度、实现靶向和缓控释给药的优点。本文通过检索近年来国内外相关文献、专利,从处方组成、制备工艺、质量控制、评价方法和研究方向等多个方面综述了喷膜剂的研究进展,为进一步优化药物的外用给药方式提供参考。

Film-forming spray is a new topical preparation with the advantages of film and sprays.It can beused for topical administration of antibacterial,analgesic,psychotropic and hormonal drugs,especially forwound protection. It has the characteristics of quantitative output, convenient administration, goodcompliance,high bioavailability,and can achieve the targeted and controlled drug delivery.By collectingthe relative literature and patent at home and abroad,we provide an overview of the advance in film-forming spray from aspects of the composition of formulation, preparation process, quality control,evaluation method and the direction of research, so as to provide some references for the furtheroptimization of drug topical delivery methods.