脂质体共递药系统用于肿瘤联合治疗的新进展

Recent advances in liposome-based co-delivery systems for combination cancer therapy

肿瘤联合治疗是临床癌症治疗的常用手段,指通过应用两种或两种以上的药物发挥协同作用从而提高抗癌效果。脂质体是一种药物载体,近年来被广泛用于多种抗癌药物的共递送。本文中,笔者主要介绍脂质体的发展以及脂质体共载体系用于癌症联合治疗的研究进展。

Combination therapy is a commonly used clinical approach for cancer treatment,in which two ormultiple agents are used to produce synergistic effects for enhanced antitcancer efficacy. Liposomes areemerging as drug carriers,and are widely applied for co-delivery of multiple drugs in recent years.In thisreview,we introduce the development of the liposomes and summarize the recent progress in the liposome-based co-delivery systems for combinatorial cancer treatment.