摘要
肿瘤联合治疗是临床癌症治疗的常用手段,指通过应用两种或两种以上的药物发挥协同作用从而提高抗癌效果。脂质体是一种药物载体,近年来被广泛用于多种抗癌药物的共递送。本文中,笔者主要介绍脂质体的发展以及脂质体共载体系用于癌症联合治疗的研究进展。
Combination therapy is a commonly used clinical approach for cancer treatment,in which two ormultiple agents are used to produce synergistic effects for enhanced antitcancer efficacy. Liposomes areemerging as drug carriers,and are widely applied for co-delivery of multiple drugs in recent years.In thisreview,we introduce the development of the liposomes and summarize the recent progress in the liposome-based co-delivery systems for combinatorial cancer treatment.
作者
王梦玥
李腾
蒋曙光
莫然
WANG Mengyue;LI Teng;JIANG Shuguang;MO Ran(Center of Advanced Pharmaceuticals and Biomaterials,China Pharmaceutical University,Nanjing 210009,China)
出处
《生物加工过程》
CAS
2018年第5期33-41,共9页
Chinese Journal of Bioprocess Engineering
基金
国家自然科学基金(81673381)
江苏省自然科学基金杰出青年基金(BK20150029)
关键词
脂质体
共递药系统
联合治疗
癌症
生物材料
liposomes
co-delivery system
combination therapy
cancer
bio?material