85岁以上结直肠癌患者术后并发症的危险因素分析

Risk factors for postoperative complications in patients over 85-year-old with colorectal cancer

目的探讨85岁以上高龄结直肠癌患者发生术后并发症的危险因素。方法回顾性分析84例85岁以上结直肠癌患者的临床资料,所有患者均采取手术治疗,探讨患者临床病理资料与术后并发症发生与否的关系。结果单因素分析结果显示,基础疾病状态、手术类型、手术时间、切除范围与术后并发症发生与否有关(均P<0.05)。进一步行多因素Logistic回归分析结果显示,合并基础疾病、开腹手术、手术时间>4 h、联合器官切除和扩大切除均为85岁以上结直肠癌患者发生术后并发症的独立危险因素(均P<0.05)。结论合并基础疾病、开腹手术、手术时间>4 h、联合器官切除和扩大切除均为85岁以上结直肠癌患者发生术后并发症的独立危险因素,临床中应重视对85岁以上结直肠癌患者术后并发症的预防干预。

Objective To analysis the risk factors for postoperative complications in patients with colorectal cancer aged over 85-year-old. Methods Clinical data of 84 cases of patients with colorectal cancer aged over 85-year-old was retrospectively analyzed.All patients underwent surgical treatment. We analyzed the relationship between the clinical pathological findings and postoperative complications. Results The univariate analysis showed that the existence of comorbidities, type of operation, operation duration and area of resection were significantly correlated with the incidence of postoperative complications（P〈0.05）. Multivariate Logistic regression analysis showed that comorbidities, laparotomy, operation duration 4 h, multiple organ resection and enlarged excision were independent risk factors for postoperative complications in patients with colorectal cancer over 85-year-old（P〈0.05）. Conclusion Comorbidies, laparotomy, operation time 4 h, multiple organ resection and enlarged excision are independent risk factors for postoperative complications in patients with colorectal cancer over 85-year-old. In clinical practice, preventative measures against postoperative complications should be implemented in patients with colorectal over 85-years-old.