体重指数和腹围指数对急性缺血性脑卒中部位和病因的影响

Influence of body mass index and abdominal circumference index on the location and etiology of acute ischemic stroke

目的探讨体重指数(BMI)和腹围指数对缺血性卒中部位和病因的影响。方法选择我院2016年1月~2017年9月收治的80例急性缺血性卒中(CIS)患者作为观察组,选择同期在我院接受检查的80例体检正常者作为对照组,测量记录两组的身高、体重和腹围,计算BMI和腹围指数,进行英国牛津郡社区脑卒中项目(OCSP)分型和TOAST分型。结果观察组的超重与肥胖亚组BMI、腹围异常亚组腹围指数均高于对照组,差异有统计学意义(P<0.05);不同BMI亚组OCSP分型中的PACI型比例(41.25%)高于TACI型(6.25%)、LACI型(30.00%)、POCI型(22.5%),差异有统计学意义(P<0.05);不同腹围指数亚组OCSP分型中,≤1 cm/kg亚组仅POCI型比例低于>1 cm/kg,差异有统计学意义(P<0.05);根据TOAST分型,分为25例(31.25%)LAA型、27例(33.75%)SAO型、13例(16.25%)CE型、7例(8.75%)SOE型和9例(11.25%)SUE型。不同BMI亚组TOAST分型中仅有SAO型比例低于LAA型,差异有统计学意义(P<0.05);不同腹围指数亚组TOAS分型中的>1 cm/kg亚组LAA型高于≤1 cm/kg亚组,差异有统计学意义(P<0.05),而>1 cm/kg亚组LAA型低于≤1 cm/kg亚组,差异有统计学意义(P<0.05)。结论CIS患者的BMI和腹围指数能影响缺血性卒中部位和病因,可作为预测病因和发病机制的重要指标。

Objective To investigate the influence of body mass index（BMI） and abdominal circumference index on the location and etiology of ischemic stroke. Methods A total of 80 patients with acute ischemic stroke（CIS） who were admitted to our hospital from January 2016 to September 2017 were selected as the observation group. 80 patients with physical examination who were examined in our hospital during the same period were selected as the control group. The body height, weight, and abdominal circumference of the two groups were calculated, and the BMI and abdominal circumference index were calculated and the Oxfordshire Community Stroke Project（OCSP） classification and TOAST classification were performed. Results The BMI of the overweight and obesity subgroup and the abdominal circumference index of the abdominal circumference abnormal subgroup were higher in the observation group than in the control group（P〈0.05）; PACI in the OCSP subtype of patients with different BMI subgroups. The proportion of type（41.25%）was higher than that of TACI type（6.25%）, LACI type（30.00%）, POCI type（22.5%）, the difference was statistically significant（P〈0.05）; OCSP classification in patients with different abdominal circumference index subgroups. In the subgroups of ≤1 cm/kg, the POCI type ratio was lower than 1 cm/kg, with a statistically significant difference（P〈0.05）; According to the TOAST classification, there were 25 cases（31.25%） of LAA type and 27 cases（33.75%） SAO type, 13 cases（16.25%） CE type, 7 cases（8.75%） SOE type and 9 cases（11.25%） SUE type. Among the TOAST subtypes with different BMI, only the proportion of SAO was lower than that of LAA, and the difference was statistically significant（P〈0.05）. The subtypes with different abdominal circumference index were subtypes of 〉1 cm/kg subtype LAA. Subgroups above ≤1 cm/kg were statistically significant（P〈0.05）, while subtypes 〉1 cm/kg subgroup were less than ≤1 cm/kg subgroup, with a statistically significant difference（P〈0.05）. Conclusion The BMI and abdominal circumference index of patients with CIS can affect the location and etiology of ischemic stroke. It can be used as an important index to predict the etiology and pathogenesis.