一例系统性红斑狼疮脑病并发可逆性后部脑病的回顾分析

Retrospective analysis of a case of neuropsychiatric systemic lupus erythematosus encephalopathy complicated with posterior reversible encephalopathy syndrome

狼疮性脑病(NPSLE)是指系统性红斑狼疮(SLE)神经系统损害相关的神经、精神表现,它可发生于系统性红斑狼疮(SLE)的任何时期,甚至表现为SLE的首发症状。临床症状呈多样化,以头痛、昏迷、抽搐、颅神经麻痹及精神症状多见。也可表现为可逆性后部脑病(PRES)的发病形式。本文对以NPSLE为首发,同时并发PRES的红斑狼疮病例进行分析,并对其临床诊治作一探讨。

Lupus erythematosus encephalopathy is a neurological and mental expression associated with nervous system damage in neuropsychiatric systemic lupus erythematosus（NPSLE）. It can occur at any time in systemic lupus erythematosus and may even appear as the first symptom of SLE. The clinical symptoms vary, including headache, coma,convulsion, cranial nerve paralysis and mental symptoms. It can also be manifested as the form of posterior reversible encephalopathy syndrome（PRES）. This article analyzes the cases of patients with the first symptom of NPSLE complicated with PRES, and discuss clinical diagnosis and treatment.