某院精神分裂症患者使用心境稳定剂的情况调查

An Investigation of Mood Stabilizers Application on Schizophrenics in A Hospital

目的:为了解笔者所在医院精神分裂症患者使用心境稳定剂的情况,并评价其使用合理性。方法:对2018年6月7日在笔者所在医院住院的精神分裂症患者精神药物应用状况进行调查,所调查对象均符合ICD-10诊断标准。结果:在所有精神分裂症患者中合并应用心境稳定剂者占28.6%,其中丙戊酸盐者占24.6%;以应用丙戊酸钠多(占15.1%),碳酸锂应用最少,占1.5%。199例精神分裂症患者中使用奥氮平合并心境稳定剂者的最多,共36例,其次是利培酮及氯氮平,喹硫平次之,而奋乃静、氨磺必利则占少数,其中包含部分联用两种抗精神病药物。结论:心境稳定剂在我院精神分裂症患者中使用广泛,且使用剂量均在安全范围。

Objective：To grasp the situation of mood stabilizers application on schizophrenics in a hospital and evaluate their usage rationality.Method：An investigation on the use of psychotropic drugs in schizophrenic patients hospitalized in the author＇s hospital on June 7,2018 was carried out.All the respondent smet the ICD-10 diagnostic criteria.Result：Among all the schizophrenic,28.6% were combined with mood stabilizers,Of which valproate accounts for 24.6%（the most application is sodium valproate,accounting for 15.1%）,the least application is lithium carbonate（accounts for 1.5%）.Among 199 schizophrenic patients,36 were treated with olanzapine combined with mood stabilizers,followed by risperidone and clozapine,followed by quetiapine,while perphenazine and amisulpride were in the minority,including some combination of two antipsychotic drugs.Conclusion：Mood stabilizers are widely applied in schizophrenic patients in our hospital,and the dosage is safe.