深度水解蛋白配方奶喂养对极低出生体重和超低出生体重婴儿生长发育的影响

Impact of Extensively Protein Hydrolyzed Formula Milk in Very Low Birth Weight and Extremely Low Birth Weight Infants

目的:分析讨论对极低出生体重和超低出生体重婴儿采用深度水解蛋白配方奶喂养的实际影响和临床价值。方法:选取笔者所在医院2016年9月-2018年1月极低出生体重和超低出生体重婴儿44例,根据入院先后将其均分为两组,每组22例,对照组给予婴儿标准早产儿配方奶;观察组给予婴儿深度水解蛋白配方奶。比较两组婴儿1周胃残留总次数、最大胃残留量、平均每天体重增长量和1周体重增长量。结果:观察组1周胃残留总次数和最大胃残留量明显低于对照组(P<0.05)。观察组平均每天体重增长量和1周体重增长量明显高于对照组(P<0.05)。结论:对极低出生体重和超低出生体重婴儿采用深度水解蛋白配方奶喂养可以显著降低1周胃残留总次数和最大胃残留量,提高平均每天体重增长量和1周体重增长量,可在各大医院中进行推广使用。

Objective：To discuss the clinical value of extensively protein hydrolyzed formula（ePHF） milk in very low birth weight and extremely low birth weight infants.Method：44 very low birth weight and extremely low birth weight infants treated from October 2016 September 2018 January were selected.The subjects were assigned to control group and observation group according to the registration number,22 cases each group.The infants took the standard formula milk or extensively protein hydrolyzed formula milk,respectively.The overall frequency of one-week gastric residuals,maximized gastric residual volume,average daily weight gains and one-week weight gains were probed.Result：The overall frequency of one-week gastric residuals and maximized gastric residual volume in the observation group were significantly reduced,had significant difference between two groups（P〈0.05）;the average daily weight gains and one-week weight gains in the observation group were higher than control group（P〈0.05）.Conclusion：The extensively protein hydrolyzed formula milk can remarkably reduce the overall frequency of one-week gastric residuals and maximized gastric residual volume,and increase the average daily weight gains and one-week weight gains.It shall be widely applied in clinical practice.