草酸艾司西酞普兰片联合喹硫平治疗广泛性焦虑障碍的效果观察

Efficacy of Escitalopram Oxalate Tablets Combined with Quetiapine in the Treatment of Generalized Anxiety Disorder

目的:研究治疗广泛性焦虑障碍患者采用草酸艾司西酞普兰片联合喹硫平的临床效果。方法:选取笔者所在医院2016年11月-2017年11月所收治的广泛性焦虑障碍患者96例,根据患者入院时间分为研究组和参照组,每组各48例,参照组患者给予草酸艾司西酞普兰片治疗,研究组患者在此基础上联合喹硫平治疗,比较2组患者治疗效果以及不良反应。结果:研究组患者治疗总有效率93.75%,显著高于参照组患者的72.91%,组间对比差异有统计学意义(P<0.05),研究组患者不良反应发生率4.17%,显著低于参照组患者的29.16%,组间对比差异有统计学意义(P<0.05),研究组患者治疗后汉密尔顿焦虑量表评分显著低于参照组,组间对比差异有统计学意义(P<0.05)。结论:采用草酸艾司西酞普兰片联合喹硫平治疗广泛性焦虑障碍患者具有明显临床效果,能够有效缓解患者焦虑障碍,并且患者治疗后不良反应也相对较少。

Objective：To study the clinical effect of combination of Escitalopram Oxalate Tablets and Quetiapine on the treatment of patients with generalized anxiety disorder.Method：Selected 96 cases of patients with generalized anxiety disorder from November 2016 to November 2017,according to the patients in hospital time was divided into research group and control group,each group of 48 cases,control group patients used Escitalopram Oxalate Tablets treatment,patients in research group used Quetiapine treatment on the basis of the control group.Compared patients of two groups therapeutic effect and adverse reactions.Result：Total effective rate of research group 93.75% was significantly higher than that of control group 72.91%,existed statistical significance（P〈0.05）.Incidence of adverse reactions of research group 4.17% was significantly lower than control group 29.16%,differences was significant（P〈0.05）.After treatment,patients Hamilton anxiety scale scores of research group significantly lower than that of control group with a significant difference between two groups（P〈0.05）.Conclusion：Using Escitalopram Oxalate Tablets combined Quetiapine in the treatment of generalized anxiety disorder has clinical effect,can effectively relieve patients＇ anxiety disorders,and adverse reactions after treatment in patients with relatively small.