血管紧张素Ⅱ受体拮抗剂联合中成药治疗慢性肾炎蛋白尿的研究进展

Advances in Research of Angiotensin II Receptor Antagonist Combined with Chinese Patent Medicine in the Treatment of Chronic Nephritis Proteinuria

慢性肾炎基本临床表现为蛋白尿、血尿、高血压、水肿,其中蛋白尿是加速肾小球硬化、促进肾功能恶化的重要因素之一,且蛋白尿水平越高,导致肾脏病进展的速度越快,因此积极降低蛋白尿是肾脏病治疗的关键。血管紧张素Ⅱ受体拮抗剂除降压作用外,还有降低患者蛋白尿水平及肾脏保护作用,为进一步减少慢性肾炎蛋白尿,在应用ARB基础上加用中成药亦可获得疗效进行综述。

The basic clinical manifestations of chronic glomerulonephritis are proteinuria,hematuria,hypertension,edema,among which proteinuria is one of the important factors to accelerate glomerulosclerosis and promote the deterioration of renal function,and the higher the level of proteinuria,the faster the progress of kidney disease.Therefore,active reduction of proteinuria is the key to the treatment of kidney disease.Angiotensin II receptor antagonists,in addition to antihypertensive effect,also reduce the level of proteinuria and renal protection in patients,in order to further reduce chronic nephritis proteinuria,the use of ARB based on the addition of proprietary Chinese medicine can also be obtained.