胃癌合并2型糖尿病术后血糖改善的临床观察

Clinical Observation of Postoperative Blood Glucose Improvement in Patients with Gastric Cancer Complicated with Type 2 Diabetes Mellitus

目的探讨胃癌合并2型糖尿病术后患者血糖的变化。方法选取我科2015年1月~2016年6月收治的52例胃癌合并T2DM的患者,均采用胃癌根治术(Roux-en-Y吻合术),回顾性分析患者空腹血糖、餐后2 h血糖及糖化血红蛋白含量情况。结果所有患者的身体质量指数(BMI)均<30 kg/m2,术后空腹血糖、餐后2 h血糖及糖化血红蛋白含量均较术前改善(P<0.05),患者术后均随访12个月,52例患者中痊愈18例,有效30例,无效4例,临床有效率为92.31%。结论 BMI<30 kg/m2的胃癌伴T2DM的患者采用Roux-en-Y吻合术治疗,血糖改善效果较好。

Objective To investigate the changes of blood glucose in patients with gastric cancer complicated with type 2 diabetes mellitus.Methods A total of 52 patients with gastric cancer and T2DM admitted to our department from January 2015 to June 2016 were enrolled.All patients underwent radical gastrectomy（Roux-en-Y anastomosis）.The patients were analyzed retrospectively for fasting blood glucose,2h postprandial blood glucose and glycosylated hemoglobin.Results The body mass index（BMI）of all patients was〈30kg/m2.The postoperative fasting blood glucose,postprandial 2h blood glucose and glycosylated hemoglobin levels were improved compared with preoperative（P〈0.05）.All patients were followed up for 12 months.Among the 52 patients,18 were cured,30 were effective,and 4 were ineffective.The clinical effective rate was 92.31%.Conclusion Patients with gastric cancer and T2DM with BMI 〈30 kg/m2 were treated with Roux-en-Y anastomosis.The effect of blood glucose improvement was better.