甘精胰岛素联合瑞格列奈治疗2型糖尿病的临床疗效观察

李锋Clinical Observation on the Treatment of Type 2 Diabetes With Insulin Glargine and Repaglinide

目的分析甘精胰岛素联合瑞格列奈治疗2型糖尿病的临床效果。方法选取2017年1月22日—2018年2月25日我院收治的2型糖尿病患者80例作为研究对象。实施随机颜色球抽取的方式,将其分为两组。两组患者分别给予甘精胰岛素、甘精胰岛素联合瑞格列奈治疗,对比两组血糖达标时间、胰岛素用量、血糖数值情况。结果观察组血糖达标时间为(8.71±3.33)d、胰岛素用量为(15.54±5.69)U/d、FPG为(6.21±1.11)mmol/L、2hPG为(8.12±2.36)mmol/L、HbAlc为(6.64±1.02)%,各指标数据与对照组比较,差异均具有统计学意义(P<0.05)。结论甘精胰岛素联合瑞格列奈治疗2型糖尿病具有较为显著的疗效,可改善患者血糖数值。

Objective To analyze the clinical effect of insulin glargine combined with repaglinide in the treatment of type 2 diabetes. Methods 80 cases of patients with type 2 diabetes mellitus admitted to our hospital from January 22, 2017 to February 25, 2018 were selected as study subjects. The method of random color ball extraction is implemented and divided into two groups. The two groups were treated with insulin glargine, insulin glargine combined with repaglinide. The blood glucose reaching standard time, insulin dosage and blood sugar value were compared between the two groups. Results In the observation group, the time of blood glucose reaching the standard was （8.71±3.33） d, the dosage of insulin was （15.54±5.69） U/d, FPG was （6.21±1.11） mmol/L, 2hPG was （8.12±2.36） mmol/L, and HbAlc was （6.64±1.02）%. There were signifcant differences between the two groups （P 〈 0.05）. Conclusion Insulin glargine combined with repaglinide has a signifcant effect on the treatment of type 2 diabetes, which can improve the blood glucose value of patients.