观察盐酸坦索罗辛与抗感染药物结合治疗慢性前列腺炎的疗效

The curative effect of tamsulosin hydrochloride combined with anti-infective drugs in the treatment of chronic prostatitis

目的:探究盐酸坦索罗辛联合抗感染药物治疗慢性前列腺炎的临床疗效。方法:选择2016年4月至2017年4月南充市中心医院收治的慢性前列腺炎患者80例,按照入院顺序分为对照组和观察组两组实施对比研究,每组40例。对照组给予左旋氧氟沙星治疗,观察组在对照组基础上联合给予盐酸坦索罗辛治疗。观察两组治前的WBC计数、最大尿流量、CPSI评分、临床治疗效果、生活质量评分。结果:治前后两组患者WBC计数、最大尿流量、CPSI评分均得到明显改善,治疗前后组内比较均存在统计学差异,且治疗后组间比较也存在统计学差异,观察组WBC计数、CPSI评分均显著低于对照组,最大尿流量显著大于对照组,P <0. 05。经临床治疗效果判定,在显效、有效的患者方面,观察组分别有20例和17例,对照组分别有15例和16例。组间对比总有效率可得差异存在统计学意义,观察组总有效率显著高于对照组,(92. 50%VS77. 50%,P <0. 05)。治疗后两组患者生活质量各项指标评分均明显提高,但观察组的治疗后评分显著高于对照组,(P <0. 05)。结论:观察盐酸坦索罗辛联合抗感染药物治疗慢性前列腺炎效果显著,可以更好的改善患者的临床症状,提高治疗有效率,并更好的改善患者的生活质量。

Objective：To explore clinical efficacy of tamsulosin hydrochloride combined with anti-infective drugs in the treatment of chronic prostatitis. Methods：80 patients with chronic prostatitis in Nanchong Central Hospital from April 2016 to April 2017 were divided into control group and observation group according to the order of adnfission, 40 eases in each group. The control group was given levofloxaein treatment, while the observation group was given tamsulosin hydroehloride combined levofloxaein treatment. The WBC count, maximmum urinary flow rate, CPSI score, clinical treatment effect and quality of life score were observed before and after treatment in the two groups. Results：The WBC count, maximmum urine flow, CPSI score before and after treatment were significantly improved in the two groups, with statistically significant difference between before and after treatment; the WBC count and CPSI score of observation group was significantly lower and the maximum urinary flow was significantly higher in the observation group than those in the control group after treatment, with statistically significant difference between the two groups （P 〈 0.05）. According to the clinical therapeutic effect, there were 20 eases and 17 eases markedly effective and effective in the observation group, and 15 eases and 16 eases in the control group respectively. The total effective rate of the observation group was significantly higher than that of the control group （92. 50% vs 77. 50% ）, with statistically significantdifference between the two groups （ P 〈 0.05 ）. After treatment, the quality of life scores of the two groups were significantly improved, but the score of the observation group was significantly higher than that of the control group （ P 〈 0. 05 ）. Conclusions ： Tamsulosin hydroehloride combined with anti-infeerive drugs is of remarkable effect in the treatment of chronic prostatitis, which can improve the elinieal symptoms of patients, improve the treatment efficiency, and improve the quality of life of patients.