GDD患儿的主要高危因素、临床特征及预后

The Main Risk Factors,Clinical Features and Prognosis of Children with GDD

目的:探讨儿童全面性发育落后(GDD)患儿的主要高危因素、临床特征及预后情况,为临床早期诊断、干预提供依据。方法:选取某院收治的181例GDD患儿,分析其高危因素、临床特征及预后情况,随访2年,期间持续干预治疗,并用χ2检验GDD患儿的高危因素及预后。结果:高危因素为新生儿窒息、宫内发育迟缓、早产、宫内窘迫、妊娠高血压病,经2年随访,已正常39例,GDD患儿95例,经干预均有好转;主要危险因素为宫内发育迟缓、宫内窘迫、新生儿窒息。结论:GDD患儿病因多且复杂,预后差,患儿临床特征不同,其病因、预后也存在差异。

Objective： To explore the main risk factors, clinical features and prognosis of children with comprehensive developmental and backward development （GDD）, and provide evidence for early clinical diagnosis and intervention. Methods： Selected 181 cases of children with GDD in a hospital, analyzed its risk factors, clinical characteristics and prognosis, followed up for 2 years, continued intervention during treatment, and inspected the risk factors and prognosis of GDD children by χ ^2 . Results： Risk factors： neonatal asphyxia, intrauterine retardation, premature delivery, intrauterine distress, gestational hypertension, after 2 years of follow-up, 39 cases had been normal, after the intervention 95 cases of children with GDD had gone better.Main risk factors： intrauterine growth retardation, intrauterine distress, newborn asphyxiation. Conclusion： The etiology of children with GDD is numerous and complicated, with poor prognosis and different clinical characteristics of children, the etiology and prognosis of children are also different.