山东市售秦艽饮片质量评价

Quality Analysis of Gentiana Commercially Availabled in Shandong Province

目的考察山东市售秦艽饮片质量。方法依据《中国药典》2010年版一部,对39批秦艽样品进行了性状、TLC、HPLC等定性、定量分析。结果检测的39批样品中,各项指标均符合规定的有28批;薄层鉴别不符合规定的有7批;浸出物不符合规定的有2批;含量测定不符合规定的有11批;不合格率28%。结论市售秦艽饮片不合格率较高,掺假造假现象仍较严重,亟需加强对中药材饮片市场的监管力度,确保临床用药安全有效。

OBJECTIVE To evaluate the quality of gentiana commercially availabled in Shandong Province. METHODS The 39 batches of Typhae pollen were quantified and qualified by characteristic determination,microscopic analysis,TLC and HPLC methods according to Chinese Pharmacopoeia（2010）. RESULTS Among the 39 batches of tested samples,28 batches were determined to meet the pharmaceutical standard,7 batches were unqualified substandard result of TLC,2 batches were unqualified substandard result of content the extract,11batches were unqualified substandard result of determination,and the unqualified sample rate was 28%. CONCLUSION The unqualified sample rate was high of gentiana commercially availabled in Shandong Province,the quality was poor,reinforce the supervise potency dimension is necessary to ensure the safety and efficacy of clinical medication.