不同镇静镇痛策略辅助治疗机械通气重症手足口病患儿的研究

Different Sedative and Analgesic Strategies in the Treatment of Severe HFMD Patients with Mechanical Ventilation

目的使用两种镇静镇痛策略对机械通气重症手足口病患儿进行辅助治疗后,观察两种方法对患儿所产生的疗效。方法随机选取自2016年3月～2017年4月在本院接受重症手足口病诊治并为其进行机械通气治疗的68例患儿,根据镇静镇痛的策略将其均分为对照组和观察组,对照组患儿的镇静镇痛策略为咪达唑仑,观察组患儿的镇静镇痛策略为咪达唑仑联合芬太尼,对比分析两组患儿的镇静程度评分(Ramsay评分)以及住院情况。结果两组患儿在镇静后的Ramsay评分都有所升高,但观察组患者Ramsay评分升高的幅度较大,对照组患儿的ICU住院时间、机械通气时间以及总住院时间都比观察组长,差异具有统计学上的意义。结论为重症手足口病患儿进行机械通气治疗的同时,采用咪达唑仑联合芬太尼为患儿进行镇静镇痛的辅助治疗,可以起到非常好的镇静效果,减缓患儿的疼痛感,具有被推广至临床上并应用的价值。

Objective To observe the curative effect of the two methods on the treatment of children with severe heart and mouth disease with mechanical ventilation by using two kinds of sedative analgesic strategies. Methods Sixty-eight children with severe hand, foot and mouth disease were treated in our hospital from March 20 to April 2017, and were divided into control group according to the strategy of sedation and analgesia And the observation group, the control group of children with sedative analgesic strategy for the midazolam, observation group of children with sedative analgesic strategy for midazolam combined with fentanyl, comparative analysis of the two groups of children with the degree of sedation score（Ramsay Score） and hospitalization. Results The Ramsay scores of the two groups increased after sedation, but the Ramsay score in the observation group was higher than that in the control group, and the ICU hospitalization time, mechanical ventilation time and total hospitalization time Observation group leader, the difference has a statistical significance. Conclusion The treatment of children with severe hand, foot and mouth disease at the same time, the use of midazolam combined with fentanyl for children with sedative analgesic adjuvant therapy, can play a very good sedative effect, slow down the pain in children Sense, has been extended to the clinical and applied value.