宁泌泰胶囊联合UPOINT临床分型系统个性化治疗湿热下注型慢性前列腺炎临床观察

Clinical Observation on Ningbitai Capsules Combined with Individualized Treatment of UPOINT Clinical Classification System for Chronic Prostatitis of Damp-heat Flowing Downward Type

目的:观察宁泌泰胶囊联合慢性前列腺炎临床分型系统(UPOINT)个性化治疗湿热下注型慢性前列腺炎的临床疗效。方法:将10 3例湿热下注型慢性前列腺炎患者随机分为2组,观察组52例采用宁泌泰胶囊+UPOINT个性化综合治疗;对照组51例单纯采用宁泌泰胶囊治疗;疗程均为8周,观察比较2组治疗前后传统慢性前列腺炎症状评分(NIH-CPSI)和中医证候评分变化,评价临床治疗效果。结果:治疗后,总有效率观察组为94.23%,对照组为7 8.4 3%,2组比较,差异有统计学意义(P<0.05)。治疗后,2组NIH-CPSI评分、中医证候评分均较治疗前降低(P<0.05);且观察组上述评分下降较对照组更显著(P<0.05)。结论:在宁泌泰胶囊治疗的基础上,根据UPOINT临床分型系统对慢性前列腺炎患者进行个性化治疗可以显著提高临床疗效。

Objective：To observe the clinical effect of Ningbitai capsules combined with the individualized treatment of UPOINT clinical classification system for chronic prostatitis of damp-heat flowing downward type. Methods：Divided 103 cases of patients with chronic prostatitis of damp-heat flowing downward type randomly into the observation group and the control group,52 and 51 cases in each group respectively. The observation group was treated with Ningbitai capsules combined with UPOINT comprehensive individualized treatment, while the control group was simply given Ningbitai capsules for treatment. The treatment of the two groups lasted for eight weeks. Before and after treatment,compared the changes in scores of the National Institutes of Health-Chronic Prostatitis Symptom Index（NIH-CPSI） and scores of Chinese medicine syndrome, and evaluated the clinical effect of the two groups. Results：After treatment, the total effective rate was 94.23% in the observation group and 78.43% in the control group, the difference being significant（P〈0.05）. After treatment,scores of NIH-CPSI and of Chinese medicine syndrome in the two groups were decreased when compared with those before treatment（P〈0.05）;the above scores in the observation group were decreased more significantly than those in the control group（P〈0.05）. Conclusion：Based on the treatment of Ningbitai capsules,the additional use of individualized treatment of UPOINT clinical classification system can significantly improve the clinical effect in treating patients with chronic prostatitis.