摘要
通过对近10年国内,外支气管哮喘动物建模方面实验研究的回顾与整理,总结哮喘动物模型建立及评价方面最新进展,发现过敏性哮喘模型仍是最经典与广泛复制的模型类型,而基于哮喘表型与异质性因素而提出的中性粒细胞哮喘、难治性哮喘模型的复制也取得一定进展。
By reviewing and sorting out the experimental research on animal models of bronchial asthma in the past ten years, the latest progress in the establishment and evaluation of animal models of asthma is summarized. It is found that the allergic asthma model is still the most classic and widely replicated model type, and the neutrophils based on the phenotype and heterogeneity of asthma. The replication of cellular asthma and refractory asthma has also made some progress.
作者
张睦涵
朱振刚
ZHANG Muhan;ZHU Zhengang(Tianjin University of Traditional Chinese Medicine,Tianjin 300193,China;Department of respiration,the First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine,Tianjin 300193,China)
出处
《实验动物科学》
2018年第4期83-86,共4页
Laboratory Animal Science
