1223名强制隔离戒毒人员HCV感染状况的流行病学调查

Epidemiological survey on the HCV infection among 1223 drug users

目的:了解江苏省某强制隔离戒毒所2015年-2017年收治的1223名吸毒人员HCV感染现状、吸毒方式、行为特征等和HCV感染的关系,为制定干预措施提供科学依据。方法:以江苏省内某强制隔离戒毒所2015年-2017年收治的男性吸毒人员1223名作为调查对象,制定统一的调查问卷进行调查,并采集静脉血检测抗-HCV抗体和肝功能等指标。结果:1223名吸毒人员中总的抗-HCV抗体阳性率是18.9%,毒品滥用的种类、方式、滥用时间长短、性伴侣数、安全套使用情况等是HCV感染率高低的重要影响因素。注射吸毒者的阳性率为61.4%,显著高于烫吸17.4%(χ~2=53.750,P=0.000)。共用吸毒器具者HCV感染率显著高于不共用者(χ~2=7.311,P=0.007)。有5个以上性伴侣者HCV感染率(38.6%)显著高于有单个性伴侣的感染率(6.5%)(χ~2=92.902,P=0.000)。结论:江苏省某强制隔离戒毒所吸毒人群的HCV感染率较高,丙型肝炎患病率高,肝功能损害严重,注射吸毒、共用注射器、吸食海洛因、吸毒年限长、多个性伴侣、不使用安全套等会增加感染HCV的风险,应当采取综合干预措施,控制HCV的传播,降低感染率。

Objective： To describe the characteristics of HCV infection among drug users in Jiangsu compulsory rehabilitation centers from 2015 to 2017 and the effect on HCV infection from drug using behaviors,social characteristics and provide baseline data for valid intervention.Methods： Face-to-face interview by using questionnaire and serum anti-HCV antibody test were conducted among 1223 male drug users who were forced to refrain drug in Jiangsu compulsory rehabilitation centers.Results：Among 1223 drug users,the overall anti-HCV antibody positive rate was 18. 9%. The rate is significant associated with kind,method,longer duration of drug use,multiple sexual partners and not using condoms. The rate in injecting drug users accounted for 61. 4%,which was significantly higher than that in singe drug addicts（ 17. 4%）（ χ2= 53. 750,P = 0. 000）. The HCV infection rate of drug users sharing injection equipment was significant higher than that of drug users without sharing injection equipment（ χ2= 7. 311,P = 0. 007）. The infection rate of HCV with more than 5 sexual partners（ 38. 6%） is significantly higher than that of single sexual partner（ 6. 5%）（ χ2= 92. 902,P = 0. 000）.Conclusion： The study have found high HCV infection rate,high incidence of hepatitis C,and serious damage of hepatic function in drug users. Behaviors at high risk like injection of drugs,heroin abuse,sharing syringes,long duration of drug abuse,multi-sex partners,and low rate of condom use were commonly identified. Strategies and measures should be done to reduce HCV infection.