永靖县儿童脊髓灰质炎、麻疹疫苗免疫效果监测分析

Monitoring of immune effects of polio and measles vaccines on the children in Yongjing Country

目的:监测和评价永靖县1~8岁健康儿童脊髓灰质炎、麻疹疫苗免疫状况,分析上述疫苗的保护率,为实施预防接种工作提供科学依据。方法:通过酶联免疫吸附试验(ELISA)检测1~8岁健康儿童血清中脊髓灰质炎、麻疹IgG抗体,比较分析不同地区、人群疫苗保护率。结果:永靖县1~8岁儿童脊髓灰质炎和麻疹疫苗的免疫效果明显,抗体阳转率均达98%。1岁组抗体阳性率低于其他各组。结论:永靖县1~8岁健康儿童脊髓灰质炎、麻疹的抗体水平已达到85%保护率的要求,应继续加强相关疫苗免疫前后抗体水平的监测工作并严格执行免疫制度。

Objective： To monitor and evaluate the basic immune condition of polio and measles vaccine on1-year to 8-year old children in Yongjing Country so as to provide scientific basis for the implementation of preventive inoculation. Methods： ELISA was applied to detecting serum IgG antibody of polio and measles in 1-year to 8-year old children. Then, the vaccination protective rate among different regions and populations were compared. Results： The immune effects of polio and measles vaccine were obviously higher,with the antibody positive transformation rate of 98%. The antibody positive rate of children in the one-year-old group was lower than that of the others. Conclusion： Polio and measles antibody levels in1-year to 8-year old health children have reached the specified standard of 85%. Monitoring work of antibody level before and after implementation of vaccination should be enhanced and immunity system should be strickly enforced in the future.