有氧运动在不稳定性心绞痛中的疗效

Efficacy of aerobic exercise on unstable angina

目的探讨不稳定性心绞痛应用有氧运动方案治疗的临床效果。方法选取2015年1月~2017年1月我院收治的100例不稳定性心绞痛患者作为研究对象,根据随机数字表法分为观察组与对照组,每组各50例。对照组单独采用常规治疗方案,观察组在常规治疗基础上配合行有氧运动。比较两组患者血清C反应蛋白(CRP)、血脂、同型半胱氨酸(Hcy)等指标。结果两组患者治疗前的Hcy、CRP及血脂比较,差异无统计学意义(P>0.05);两组患者治疗后Hcy、CRP及血脂均低于治疗前,差异有统计学意义(P<0.05),且观察组低于对照组,差异有统计学意义(P<0.05);两组患者治疗前心功能指标左室舒张末期内径(LVEDD)、舒张末期室间隔厚度(IVST)、舒张期后壁厚度(PWT)、左室射血分数(LVEF)比较,差异无统计学意义(P>0.05);两组患者治疗后LVEDD、LVST、PWT均低于治疗前,LVEF高于治疗前,差异有统计学意义(P<0.05),且观察组LVEDD、LVST、PWT低于对照组,LVEF高于对照组,差异有统计学意义(P<0.05);观察组总有效率(94%)明显高于对照组(76%),差异有统计学意义(P<0.05)。结论针对临床收治的不稳定性心绞痛患者,应用有氧运动予以治疗,可显著改善Hcy、CRP水平,增强心脏功能,提高临床总有效率,对促进患者生存质量的增强意义重大。

Objective To investigate the clinical effect of aerobic exercise regimen for unstable angina. Methods A total of 100 patients with unstable angina treated in our hospital from January 2015 to January 2017 were selected as study subjects, and divided into observation group and control group according to the random number table method,with 50 cases in each group. In the control group,routine treatment alone was used. On the basis of routine treatment,aerobic exercise was added in the observation group. The serum C-reactive protein（CRP）, blood lipids, homocysteine（Hcy） were compared between the two groups. Results There was no significant difference in the level of Hcy, CRP or blood lipid between the two groups before treatment（P〉0.05）. After treatment, Hcy, CRP and blood lipid were all lower than those before treatment, with statistical significance（P〈0.05）. The indexes in the observation group were lower than those in the control group, the differences were statistically significant（P〈0.05）. There was no significant difference in cardiac indexes such as left ventricular end-diastolic dimension（LVEDD）, interventricular septum thickness（IVST）,left ventricular ejection fraction（LVEF）, posterior wall thickness（PWT） before treatment between the two groups（P〉0.05）. After treatment, LVEDD, IVST and PWT in the two groups were lower than before treatment, while LVEF was higher than before treatment, with statistical significance（P〈0.05）. The indexes of LVEDD, IVST and PWT in the observation group were lower than those in the control group, while the LVEF was higher than that in the control group,with statistical significance（P〈0.05）. The total effectiveness rate in the observation group（94%） was significantly higher than that in the control group（76%）, the difference was statistically significant（P〈0.05）. Conclusion For patients with unstable angina in clinic, application of aerobic exercise can significantly improve the levels of Hcy and CRP, enhance cardiac function,and increase the total clinical effectiveness rate, which is of great significance to enhance patient′s quality of life.