葶苈大枣汤合桂枝茯苓丸治疗AECO PD加重期痰浊瘀肺证临床分析

Clinical Analysis on Tingli Dazao Decoction and Guizhi Fuling Pills in the Treatment of Phlegm Turbidity and Blood Stasis Lung Syndrome in Acute Exacerbation Period of AECOPD

目的探讨葶苈大枣汤合桂枝茯苓丸加味治疗对慢性阻塞性肺疾病急性加重期(AECOPD)痰浊瘀肺证患者的疗效。方法将本院2015年—2017年诊治的80例符合纳入标准的痰浊瘀肺型AECOPD患者随机分为对照组和治疗组,每组40例,对照组给予常规治疗,治疗组在常规治疗的基础上加用葶苈大枣汤合桂枝茯苓丸加味治疗,观察2组患者治疗前及治疗后的血气分析、慢阻肺评估测试(COPD As-sessment Test,CAT)、症状体征评分并进行疗效评价。结果对照组和治疗组治疗前后以及2组治疗后血气分析指标、CAT积分和症状体征评分的差异均具有统计学意义(P <0.05)。结论葶苈大枣汤合桂枝茯苓丸加味能够有效控制AECOPD的病情,缓解临床症状,同时在减轻并发症以及提高患者治疗信心方面具有重要意义。

Objective To investigate the curative effects of Tingli Dazao decoction and Guizhi Fuling pills in the treatinent of phlegm turbidity and blood stasis lung syndrome in acute exacerbation period of chronic obstructive puhnonary disease （AECOPD） . Methods Eighty patients who met with the inclusion criterias and were diagnosed as acute exacerbation of COPD with the phlegm obstructive puhnonary type between 2015 and 2017 were randomly divided into control group and treatment group, with 40 cases in each group. The control group was given routine treatment, while the treatment group was given the Tingli Dazao decoction and Guizhi Fuling pills based on the conventional treatment. The blood gas analysis, the assessment test of COPD, and the symptom scores of two groups of patients before and after treatinent were under the observation and evaluation of the curative effect. Results There was a statistically significant difference in blood gas analysis, CAT scores and symptom scores between the control group and the study group before and after treatment, as well as between the two groups （P〈0.05） . Conclusion Tingli Dazao decoction combined with Guizhi Fuling pill can effectively control AECOPD illness, alleviate the clinical symptoms, and has important significance in reducing the complications and improve patients＇ confidence.