摘要
目的:探讨青少年胃肠道炎性肌纤维母细胞瘤(Inflammatory Myofibroblastic Tumor,IMT)的临床及病理组织学特征。方法:报道5例胃肠道IMTs,结合相关文献进行复习。结果:女性2例,男性3例,年龄9~17岁,中位年龄13岁。5例术前均行B超及CT检查,考虑间质瘤。术后病理均确诊为胃肠道IMT。免疫组化肿瘤细胞均表达vimentin、actin(SM)、ALKp80,2例表达CK,而CD117、Dog-1、CD34、desmin、S-100、CD21、CD68、P53、IgG、IgG4均阴性。Ki67增殖指数3%~15%。结论:胃肠IMT临床特征似胃肠间质瘤,确诊主要依靠病理学检查,手术完全切除后注意随访。
Objective: to study the clinical and histologic feature of juvenile gastrointestinal inflammatory myofibroblastic tumor (IMT). Methods: 5 cases of gastrointestinal IMTs were reported and reviewed in combination with related literature. Results: there were 2 females and 3 males, ged from 9 to 17 years, and the median age was 13 years. B-mode ultrasound and CT examination were performed in all 5 cases before operation, and interstitial tumor was considered. Postoperative pathology was confirmed as gastrointestinal IMT. Vimentin, actin (SM) and ALKp80 were expressed in immunohistochemical tumor cells, and CK was expressed in 2 cases, while CD117, dog-1, CD34, desmin, s-100, CD21, CD68, P53, IgG and IgG4 were negative. Ki67 proliferation index is 3%~15%. Conclusion: the clinical features of gastrointestinal IMT are similar to gastrointestinal stromal tumor, and the diagnosis depends mainly on pathological examination, follow-up investigation should be stressed after complete resection.
出处
《中医临床研究》
2018年第24期109-111,共3页
Clinical Journal Of Chinese Medicine
关键词
胃肠道
青少年
炎性肌纤维母细胞瘤
临床病理学
免疫组化染色
Gastrointestinal tract
Teenagers
Inflammatory myofibroblastoma
Clinical pathology
Immunohistochemical staining