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伊立替康、奥沙利铂及氟尿嘧啶联合治疗晚期结直肠癌的临床观察 被引量:3

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摘要 目的探讨伊立替康、奥沙利铂及氟尿嘧啶联合治疗晚期结直肠癌的临床疗效。方法 70例晚期结直肠癌患者,按治疗方式不同分为研究组与对照组,各35例。对照组予以伊立替康与奥沙利铂联合治疗,研究组予以伊立替康、奥沙利铂与氟尿嘧啶联合治疗。比较两组的治疗效果。结果研究组近期的临床治疗总有效率77.14%显著高于对照组的57.14%,差异具有统计学意义(P<0.05)。研究组治疗后的生理功能评分为(57.45±6.23)分,日常生活评分为(55.70±3.87)分,认知功能评分为(63.46±7.25)分,社会功能评分为(58.43±5.13)分,情感功能评分为(62.45±3.16)分,均显著高于对照组的(45.26±7.25)、(43.16±3.28)、(50.92±5.89)、(46.88±6.14)、(53.98±4.36)分,差异具有统计学意义(P<0.05)。结论伊立替康、奥沙利铂及氟尿嘧啶联合治疗晚期结直肠癌可有效提高患者的近期治疗效果和生存质量。
作者 潘荣涛
出处 《中国实用医药》 2018年第25期103-105,共3页 China Practical Medicine
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