丁苯酞注射液联合疏血通注射液治疗急性期脑梗死的临床疗效观察及经济学分析

Study on the Clinical Efficacy and Economic of Butylphthalide Injection combined with Shuxuetong Injection for the Treatment of Acute Cerebral Infarction

目的观察和探讨丁苯酞注射液联合疏血通注射液治疗急性期脑梗死临床疗效及经济性评价。方法选择于2015年6月至2016年6月来我院治疗急性脑梗死的120例患者作为研究对象,随机分为两组,观察组和对照组,每组60例患者。对照组患者采用疏血通注射液进行治疗;观察组患者在对照组的基础上,联合丁苯酞注射液进行治疗。观察对比两组患者的临床疗效,NISS评分,ADL评分以及两组患者的成本效果对比。结果观察组的临床有效率为88.3%,显著优于对照组的73.33%,并具有统计学差异(P<0.05)。治疗前,两组患者的NISS评分,ADL评分等均无显著性差异。治疗后,观察组患者的NISS评分,治疗后30 d、60 d、180 d,观察组患者的ADL评分均显著优于对照组患者,并具有显著性差异(P<0.05)。观察组患者的成本效果比显著低于对照组患者,并且具有显著性差异(P<0.05)。结论 :丁苯酞注射液联合疏血通注射液治疗急性期脑梗死临床疗效确切并且经济成本低,显著改善急性脑梗死患者的预后,值得临床推广应用。

Objective To observe and study clinical efficacy and evaluate economic the butylphthalide injection combined with Shuxuetong injection for treatment of acute cerebral infarction clinical efficacy and economic evaluation. Methods We selected 120 cases of patients who were treated for acute cerebral infarction from June 2015 to June 2016 in our hospital as the research objects, they were randomly divided into two groups, the observation group and the control group, each group had 60 patients. The control group was treated with Shuxuetong injection treatment; based on the control group, the observation group patients combined with butylphthalide injection treatment. The curative efficacy, the NISS group, two patients with score, ADL score of the two groups were compared. Results The clinical effect of the observation group was 88.3%, which is significantly better than 73.33% of the control group, and the difference was statistically significant（P0.05）. Before treatment, the NISS score, ADL score of two groups, there were no significant differences. 30 days,60 days, 180 days after treatment, the NISS score, ADL scores of the observation group were significantly better than those of the control group, there were significant difference（P 0.05）. The cost of observation groups was lower than that of the control group, there was a significant difference（P 0.05）. Conclusion The clinical efficacy of dl-3-n-butylphthalide injection combined with Shuxuetong injection fo the treatment of acute cerebral infarction was high and the exact low economic cost, it is significantly improve the prognosis of patients with acute cerebral infarction, it is worthy of clinical application.