摘要
以含有不同取代基的芳香醛、脲(尿素、硫脲)、乙酰乙酸乙酯为反应原料,以Hf(OTf)_4为催化剂,采取"一锅煮"的方式,利用Biginelli反应合成一系列含O-和S-DHPMs化合物。
By using Hf(OTf)4 as catalyst, a series of 2-selenoxo DHPMs have been synthesized efficiently in good yields by Biginelli reaction with aromatic aldehyde, urea(urea, thiourea), ethyl acetoacetate as starting material.
作者
丁亚军
余晨蓓
陈沛然
Ding Ya-jun;Yu Chen-bei;Chen Pei-ran(College of Chemical Engineering and Biotechnology,Donghua University,Shanghai 201620;Shanghai No.2 Middle School,Shanghai 200031)
出处
《生物化工》
2018年第3期21-25,共5页
Biological Chemical Engineering
基金
国家自然科学基金资助项目(21272305)