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单克隆抗体生产中CHO细胞培养工艺研究进展 被引量：3

Discussing on CHO Cell Culturing Process of Monoclonal Antibody Production
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摘要 近年来,我国治疗性单克隆抗体产业飞速发展,CHO细胞表达系统在该行业中应用广泛,相应的细胞培养技术成为当下研究热点。本文从培养基、培养参数和工艺放大等方面入手,对CHO细胞培养工艺进行探讨。 The therapeutic monoclonal antibody industry developed rapidly in recent years, and the CHO cell expression system has been applied widely, thus the corresponding culturing technology has become a hot spot for researchers. In order to guarantee the quality, efficiency and stability of antibody production, the culturing process of CHO cells was discussed from the aspects of culture medium, parameters and scale-up.
作者 李未思 Li Wei-si(State Key Laboratory of Biotherapy,Sichuan University,Sichuan Chengdu 610000)
机构地区 四川大学生物治疗国家重点实验室
出处 《生物化工》 2018年第3期133-134,137,共3页 Biological Chemical Engineering
关键词 单克隆抗体 细胞培养 CHO细胞 Monoclonal antibody Cell culture CHO Cell
分类号 Q813.1 [生物学—生物工程]
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生物化工
2018年 第3期

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