多普勒超声对尿毒症患者左心室舒张功能的评价

Evaluation of the left ventricular diastolic function in patients with uremia by using Doppler ultrasound

目的探讨应用脉冲及频谱多普勒超声评价尿毒症患者的不同心室构型左心室舒张功能的状况,为评价其心室的舒张功能提供超声依据。方法选择尿毒症患者36例,根据不同的左心室构型分为A(左心室构型正常组)、B(左心室离心性肥厚组)、C(左心室向心性肥厚组)三组。评价左心室舒张功能,应用多普勒技术,测量左心室舒张功能参数并进行分析。结果 B组的E/A和e'值较A组显著降低(P <0. 01),C组的E/A和e'值较A组亦显著降低(P <0. 01); C组的E/e'比值较B组呈显著增高趋势(P <0. 01)。结论左心室向心性肥厚和离心性肥厚构型的左心室舒张功能均较正常降低,尤以向心性肥厚减低更为明显。

Objective To study the left ventricular diastolic function in different ventricular configurations in patients with uremia by pulse and spectral Doppler ultrasound, and to provide the basis for evaluating the degree of left ventricular diastolic dysfunction. Methods According to left ventricular configuration, a total of 36 patients with uremia were divided into A group （normal group）, B group （eccentric hypertrophy group） and C group （concentric hypertrophy group）. LV diastolic function parameters were measured by Doppler and analyzed. Results Compared with A group, the values of E/A and e＇ decreased significantly in both B and C group（P 〈0. 01 ）. E/e＇ of the patients of C group were significantly increased than those of B group （P 〈 0. 01 ）. Conclusion The left ventricular diastolic function of patients with ventricular geometry of eccentric hypertrophy and concentric hypertrophy is poor, especilly the later one.