铜陵地区社区获得性下呼吸道感染病原学分析

Etiological Analysis of Community-acquired Lower Respiratory Tract Infection in Tongling Region

目的分析铜陵地区社区获得性下呼吸道感染(LRTI)住院患者病原学分布特点;测定主要病原菌对常用药物的敏感性。方法纳入366例2016年8月—2017年12月铜陵市人民医院诊断为社区获得性LRTI(下呼吸道感染)的住院患者,收集其痰液及临床信息,用传统培养法、血清学方法检测病原体。结果 366例患者中,检测到病原体74株,主要为铜绿假单胞菌、肺炎支原体和肺炎克雷伯杆菌。5例患者(1.37%)存在2种以上病原体混合感染,其中肺炎支原体混合感染最为常见。25株铜绿假单胞菌对丁胺卡那、庆大霉素敏感率最高,均为100.00%,耐药率最高为头孢曲松,为33.00%。结论该地区社区获得性LRTI住院患者细菌检出率最高的为铜绿假单胞菌和肺炎克雷伯杆菌,非典型病原体为肺炎支原体。

Objective To analyze the etiological distribution features of community-acquired lower respiratory tract infection in Tongling region and measure the sensitivity of major pathological bacteria to the common drugs. Methods 366 cases of inpatients with community-acquired lower respiratory tract infection from August 2016 to Deeember 2017 were selected, and the sputum and clinical information were collected, and the pathology was tested by the traditional culture method and serum method. Results Of 366 cases of patients, 74 strains of pathological bacteria were tested, mainly including pseu- domonas aeruginosa, myeoplasma pneumoniae and klebsiella pneumonia, and 5 cases of patients 1.37% had the mixed in- fection of pathological bacteria more than two kinds, and the myeoplasma pneumonia mixed infection was the common, and the sensitivity rate of 25 strains of pseudomonas aeruginosa to amikaein, gentamiein was the highest 100.00%, and ceftriax-one had the highest drug-resistance rate 33.00%. Conclusion The test rates of pseudomonas aeruginosa and klebsiella pneumonia of inpatients with community-acquired lower respiratory tract infection are highest, and the atypical pathogen is the myeoplasma pneumonia.