经阴彩超宫颈癌RI值与其临床病理特征相关性分析

Correlation of RI Value and Clinicopathological Features of Vaginal Ultrasonography in Cervical Cancer

目的探讨经阴彩超检查宫颈癌的血流阻力指数(RI)与临床病理特征的关系。方法收集59例经病理证实为宫颈癌患者和50例经过经阴彩色多普勒检查的宫颈肌瘤患者,比较二者的血流及RI值,根据RI分组:RI <0. 5组、0. 5≤RI≤0. 8组与RI> 0. 8组,分析RI值与宫颈癌临床病理特征的关系。结果宫颈癌RI值明显低于宫颈肌瘤,差异具有统计学意义(P <0. 05); RI <0. 5组、0. 5≤RI≤0. 8组、RI> 0. 8组在FIGO分期、肿瘤直径、病理分级、淋巴结转移、肌层/宫旁浸润方面比较具有有统计学意义(P <0. 05); RI的AUC为0. 564(95%CI:0. 345～0. 824),当Youden指数最大值为0. 723时,对应的RI值为0. 61,将该值作为截断点,敏感性、特异性分别为80. 3%、82. 6%。结论 RI值变化与宫颈癌临床病理特征密切相关,FIGO分期越高、肿瘤直径越大、分化越低、有淋巴结转移及肌层/宫旁浸润的患者RI值越低;检测RI值对宫颈癌的诊断及判断肿瘤的恶性程度、浸润、转移情况具有重要的参考意义。

Objective To investigate the relationship between the blood flow resistance index（RI） and the clinicopathological features of cervical cancer by transvaginal ultrasonography. Methods 59 patients with cervical cancer confirmed by pathology and 50 patients with cervical myoma treated by color Doppler were selected.The blood flow and RI value,According to RI group：RI〈0.5 group,0.5≤RI≤0.8 group and RI〉 0.8 group.The relationship between RI value and clinicopathological features of cervical cancer was analyzed. Results The RI value of cervical cancer was significantly lower than that of cervical myoma（ P〈0.05）.RI〈0.5,0.5≤RI≤0.8,RI〉0.8 were significantly different in FIGO stage,tumor diameter,pathological grade,（ P〈0.05）.The AUC of RI was 0.564（95% CI：0.345-0.824）.When the Youden index was 0.723,the corresponding RI value 0.61,the value as a cut-off point,the sensitivity and specificity were 80.3% and 82.6%. Conclusion The RI value is closely related to the clinicopathological features of cervical cancer.The higher the FIGO stage,the larger the tumor diameter,the lower the differentiation,the lower the RI value in patients with lymph node metastasis and myometrial invasion.Cancer diagnosis and determine the degree of malignancy,invasion,metastasis has an important reference value.