青光眼基因治疗研究进展

Advances in gene therapy of glaucoma

青光眼是目前临床上常见的不可逆性致盲眼病之一,其危害严重,迄今尚无有效的治疗方法。近年来,大量的研究发现,其发病机制与相关基因结构和功能的异常密切相关。随着人们对青光眼发病相关基因的深入研究,以及基因治疗试验在大鼠等哺乳动物模型中的广泛开展,基因治疗将成为未来治愈青光眼的重要方向之一。因此,本文将对青光眼基因治疗的最新研究进行综述。

Glaucoma is a common and seriously harmful disease that can cause irreversible blindness, and so far there is no effective treatment to prevent the development of the disease. In recent years, a large number of studies have found that the pathogenesis is closely related to the structural and functional abnormalities of related genes. With the further research on the gene related to the pathogenesis of glaucoma, and the gene therapy trials widely carried out in mammals such as rats, gene therapy will become one of the important directions for the future treatment of glaucoma. Therefore, this article will review the latest research on gene therapy of glaucoma.