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缩宫素联合连续硬膜外阻滞麻醉对无痛分娩产妇应激反应及疼痛程度的影响 被引量:31

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摘要 目的探讨缩宫素联合连续硬膜外阻滞麻醉对无痛分娩产妇应激反应及疼痛程度的影响。方法选择要求无痛分娩产妇96例为研究对象,随机分为观察组和对照组各48例,对照组给予连续硬膜外阻滞麻醉无痛分娩,观察组在对照组用药的基础上联合应用缩宫素,比较两组应激反应、疼痛程度、产程时间等相关指标。结果宫口开3cm时、宫口开3cm时后1小时、胎儿娩出时,观察组产妇血清皮质醇(Cor)、去肾上腺素(NE)、肾上腺素(ADR)、促肾上腺皮质激素(ACTH)含量等均明显低于对照组(t=4.398~12.124,P<0.05),VAS评分均明显低于对照组(t=4.854~6.161,P<0.05);观察组第1产程、第2产程、第3产程均明显短于对照组,产后2小时出血量明显低于对照组,新生儿Apgar评分明显高于对照组(t=2.076~11.090,P<0.05)。结论缩宫素联合连续硬膜外阻滞麻醉有助于缓解无痛分娩产妇疼痛程度,促进子宫收缩,减少术后出血量,可能与下调血清应激激素水平有关。
机构地区 北京航天总医院
出处 《中国临床医生杂志》 2018年第8期975-977,共3页 Chinese Journal For Clinicians
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