重视眼内组织活体检查的临床应用

Significance of intraocular biopsy in the diagnosis and treatment of eye diseases

眼内组织活体检查是眼病理学诊断的重要方法，对非典型眼部病变的诊断、治疗策略选择、预后判断等具有重要的指导意义。目前我国尚未广泛开展眼内组织活体检查，这与眼科医师对眼内组织活体检查技术重视不足、取材及标本制作技术不规范、眼部并发症及眼球解剖结构限制等因素有关。本文通过分析目前我国眼内组织活体检查存在的问题，指出眼科医师应在提高认识的基础上，严格把握眼内组织活体检查的适应证，加强取材操作的规范性，以提高眼内组织活体检查的成功率。临床医师应与病理科医师密切配合，以便眼内组织活体检查技术对眼部病变的诊断、治疗及预后判断发挥重要指导作用，共同提高眼部疾病的诊断和治疗水平。（中华跟群杂志，2018，54641—644）

Intraoeular biopsy is an important method of preoperative ophthalmic diagnosis. It can provide an objective basis for precise treatment of diseases, and has important guiding significance in the diagnosis of eye diseases, the selection of treatment strategies and the anticipation of prognosis. Eye biopsy technology has not yet been widely carried out to date in our country, and ophthalmologists should attach great importance to the role of intraocular biopsy in the diagnosis and treatment of eye diseases. Ophthalmologists should particularly improve the success rate of intraocular biopsy by strengthening the standardization of material sampling; facilitate the guiding effect of eye biopsy on the diagnosis, treatment and prognosis of eye diseases through efficient cooperation between clinician and pathologist; to improve the sensitivity and specificity of intraocular biopsy through organized combination of traditional cellular pathology with molecular pathology. （Chin J Ophthalmol, 2018, 54： 641-644）