用参苓白术散治疗腹泻的效果研究

Effect of shenlingbaizhu powder for diarrhea

目的:探讨用参苓白术散治疗腹泻的临床效果。方法:将2016年6月至2017年6月期间青川县中医医院收治的60例腹泻患者作为研究对象。将这60例患者随机平均分为对照组和观察组。为两组患者均使用蒙脱石散进行治疗,在此基础上,为观察组患者加用参苓白术散进行治疗。然后,比较两组患者的治疗效果、各项炎症因子的水平、各项临床症状消失的时间及其不良反应的发生率。结果:经过治疗,与对照组患者相比,观察组患者治疗的总有效率更高,其TNF-α(肿瘤坏死因子)的水平、IL-6(白介素-6)的水平和IL-8(白介素-8)的水平均更低,其止泻的时间和腹痛症状消失的时间均更短,P<0.05。结论:联用蒙脱石散和参苓白术散治疗腹泻的效果更好,可迅速为患者止泻,并可降低其体内炎症因子的水平,缩短其治疗的时间,且安全性高。

Objective： To explore the clinical effect of shenling baizhu powder in treating diarrhea. Methods： 60 patients with diarrhea admitted to qingchuan county TCM hospital from June 2016 to June 2017 were studied. The 60 patients were randomly divided into a control group and an observation group. Both groups were treated with montmorillonite powder. On this basis, the observation group was treated with shenling baizhu powder. Then, the therapeutic effect, the levels of various inflammatory factors, the time of each clinical symptom disappearance and the incidence of adverse reactions were compared between the two groups. Results： after treatment, compared with the control group, the patients in the observation group had a higher overall therapeutic efficiency, with lower levels of TNF-（tumor necrosis factor）, il-6（interleukin-6）, and il-8（interleukin-8）. The duration of antidiarrheal and the disappearance of abdominal pain symptoms was shorter, P〈0.05. Conclusion： the combination of montmorillonite powder and shenling baizhu powder is more effective in treating diarrhea, which can stop diarrhea rapidly for patients, reduce the level of inflammatory factors in their bodies, shorten the treatment time, and has high safety.