顺铂同步放化疗用于中晚期宫颈癌患者的可行性分析

Feasibility of cisplatin concurrent chemoradiotherapy for patients with middle and late cervical cancer

目的:探讨奈达铂同步放化疗及顺铂同步放化疗治疗中晚期宫颈癌患者的临床效果及不良反应。方法:收治中晚期宫颈癌患者84例,随机分成对照组和观察组,每组42例。对照组中晚期宫颈癌患者采用奈达铂同步放化疗,观察组中晚期宫颈癌患者采用顺铂同步放化疗。结果:治疗后,两组中晚期宫颈癌患者治疗有效率、3年生存率、局部复发率、远处转移率差异无统计学意义(P>0.05)。结论:顺铂同步放化疗能提升中晚期宫颈癌患者的近期疗效,患者治疗后远期疗效较好。

Objective：To explore the clinical effects and adverse reactions of nedaplatin concurrent chemoradiotherapy and cisplatin concurrent chemoradiotherapy for patients with middle and late cervical cancer.Methods：84 patients with middle and late cervical cancer were selected,they were randomly divided into the control group and the observation group.The control group was treated with nedaplatin concurrent chemoradiotherapy,the observation group was treated with cisplatin concurrent chemoradiotherapy.Results：After treatment,there was no significant difference in the effective rate,the 3 years survival rate,the local recurrence rate and the distant metastasis rate between the two groups（P〈0.05）.Conclusion：Cisplatin concurrent chemoradiotherapy can improve the short-term curative effect for patients with middle and late cervical cancer,and the long-term effect was better.