颅内血管周细胞瘤20例临床病理分析

Clinicopathological analysis on 20 cases of intracranial perivascular pericytoma

目的:探讨颅内血管周细胞瘤的临床病理特征。方法:收治颅内血管周细胞瘤患者20例,经HE、EnVision法以及网状纤维染色法进行诊断,分析病理组织学形态特征和免疫组化特点。结果:PR均为阴性,Bcl-2、Vimetin均为阳性,CD34阳性18例(90.00%),EMA部分阳性3例(15.00%)。结论:血管周细胞瘤属于临床较为罕见的中枢神经系统肿瘤,缺乏特异性的影像学特征和临床表现,因此必须依赖病理学和免疫组化法进行确诊。

Objective：To investigate the clinicopathological features of intracranial hemangioma.Methods：20 patients with intracranial perivascular pericytoma were treated by HE,EnVision and reticular fiber staining,the morphological and immunohistochemical features of the histopathology were analyzed.Results：PR was negative,Bcl-2 and Vimetin were positive,CD34 positive in 18 cases（90%）,EMA positive in 3 cases（15%）.Conclusion：Pericytoma tumor is a rare central nervous system tumor.It lacks specific imaging features and clinical manifestations.Therefore,it is necessary to rely on pathology and immunohistochemical method for diagnosis.