抗菌肽与结核分枝杆菌感染的研究进展

Research progress of antimicrobial peptides and infection of Mycobacterium tuberculosis

抗菌肽（AMPs）是一种由先天免疫系统组成的小、阳离子、双亲性肽类物质，具有较强杀菌作用及免疫调节活性，已在抗结核方面展示出特殊的优势。由于其不同于传统的抗结核药物，有可能成为治疗结核病的新途径。文中就AMPs与结核分枝杆菌感染的研究进展作一综述。

Antimicrobial peptides （AMPs） are small, cationic and amphipathic peptides that comprise a section of the innate immune system. They have strong bactericidal and immunomodulatory activities and have shown special advantages in anti-tuberculosis. Due to its difference with traditional anti- tuberculosis drugs, it may be a new way for treatment of tuberculosis. This article reviews the research progress of antimicrobial peptides and infection of Mycobacterium tuberculosis.