经腹羊膜腔灌注术治疗31例早产胎膜早破的效果及对潜伏期的影响分析

Effect of Transabdominal Amnioinfusion in the Treatment of Preterm Premature Rupture of Membranes in 31 Cases and the Influence on the Latency

目的探析经腹羊膜腔灌注术治疗早产胎膜早破(PPROM)的效果及对潜伏期的影响。方法选取2015年4月—2017年10月间在洛阳市妇女儿童医疗保健中心治疗PPROM的妊娠妇女62例,按随机数字表法将患者均分为灌注组与对照组。对照组予以静脉补液治疗,灌注组予以B超下经腹羊膜腔穿刺,灌注平衡盐溶液治疗,分别观察两组患者治疗总有效率、胎膜早破潜伏期、孕周及围生期感染率。结果灌注组与对照组总有效率分别为93. 55%与64. 52%,灌注组明显高于对照组(P <0. 05);灌注组胎膜早破潜伏期及孕周均明显长于对照组(P <0. 05);灌注组与对照组围生期感染率分别为12. 90%和16. 13%,组间比较差异无统计学意义(P> 0. 05)。结论采用经腹羊膜腔灌注术治疗PPROM效果确切,可明显延长胎膜早破潜伏期及孕周,不会增加母婴感染风险。

Objective To explore the effect of transabdominal amnioinfusion in the treatment of preterm premature rupture of membranes （PPROM） and the influence on the latency. Methods A total of 62 pregnant women with PPROM treated in the hospital from April, 2015 to October, 2017 were selected. By the random number table method, they were divided into the infusion group and the control group, with 31 cases in each group. The control group was treated with intravenous fluid infusion, and the infusion group was treated with transabdominal anmioeentesis under B- ultrasound and infusion of balanced salt solution. The total effective rates of treatment, latency of premature rupture of membranes, gestational weeks and perinatal infection rates of two groups were observed. Results The total effective rate of the infusion group was significantly higher than that of the control group （ 93.55 % vs 64.52% ） （P 〈 0. 05 ）. The latency of premature rupture of membranes and gestational weeks of the peffusion group were significantly longer than those of the control group （ P 〈 0. 05 ）. There was no significant difference between the infusion group and the control group in the perinatal infection rate （ 12. 90% vs 16. 13% ） （ P 〉 0. 05 ）. Conclusion Transabdominal amnioinfusion in the treatment of PPROM can significantly prolong the latency of premature rupture of membranes and gestational weeks, without increasing the risk of maternal and neonatal infections.