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Th17/IL-17在急性肺损伤中的研究进展 被引量:7

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摘要 Th17细胞(Th17)是CD4+T细胞的一个亚群,因高表达白介素-17(IL-17)而得名。IL-17受体(IL-17R)分布广泛,几乎所有类型细胞均可表达。IL-17与其受体结合后被活化,可召募中性粒细胞、巨噬细胞等多种炎性细胞,加重局部炎症反应,在各种感染性疾病中发挥着重要作用。感染是急性肺损伤(ALI)最主要的致病因素,Th17和IL-17在ALI中的作用,也受到了越来越多的关注。
作者 丁琦 黄建安
出处 《临床肺科杂志》 2018年第11期2111-2113,共3页 Journal of Clinical Pulmonary Medicine
基金 苏州市技术创新项目(No SYSD2015107)
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