单纯全尾状叶切除术治疗巨块型肝癌(直径≥10 cm)的疗效

Efficiency of isolated caudate lobe resection for huge hepatocellular carcinoma(10 cm or larger in diameter)

目的:探讨尾状叶巨块型肝癌(直径≥10 cm)行单纯全尾状叶切除手术的可行性及疗效。方法:回顾性分析2001年1月至2011年12月27例单纯全尾状叶切除的巨块型肝癌患者的临床资料。结果:27例患者均顺利手术,无死亡病例,平均手术时间288 min,平均出血量2 260 mL,44%的患者出现了术后并发症,经积极处理均顺利出院。术后1,3,5年的总生存率分别是80.2%,52.1%,27.1%。结论:尾状叶巨块型肝癌行单纯全尾状叶切除安全有效。

Objective： To explore the feasibility and effi cacy of isolated caudate lobe resection for caudate lobe in huge hepatocellular carcinoma（10 cm or larger in diameter）. Methods： Clinical data of 27 patients with hepatocellular carcinoma larger than 10 cm who underwent isolated caudate lobe resection from January 2001 to December 2011 were retrospectively analyzed. Results： All the patients successfully completed the operation. Th ere was no postoperative death. Median operative time was 288 min, and the estimated intraoperative blood loss was 2 260 mL. Postoperative morbidity rate was 44.4%. The patients were discharged successfully after active treatment. Overall survival rates at 1, 3, and 5 years were 80.2%, 52.1%, and 27.1%, respectively. Conclusion： Isolated caudate lobe resection is safe and effective for caudate lobe huge hepatocellular carcinoma.