摘要
作为一种新型的微纳制造技术,电纺直写对于生物组织工程而言意义重大,而纤维间的黏结力直接影响最终组织支架的稳定性。本研究采用生物可降解材料聚己内酯(PCL),通过自行设计的熔体电纺三维可控成型设备进行直写电纺,探究了喷头温度、冷热纤维的搭接间隔时间以及环境温度对纤维黏结效果的影响,并用热重分析仪(TGA)进行表征。研究表明:随着喷头温度的升高,纤维间的黏结力先逐渐增大,在出现轻微波动后又呈减小趋势,其中在190-210℃区间内黏结效果最佳;随冷热纤维搭接时间间隔的延长,纤维间的黏结效果不断下降;此外,环境温度对纤维黏结效果的影响较大。
As a new type of micro-nano manufacturing technology, electrospinning direct writing has the great significance to biological tissue engineering. The adhesive force between fibers directly affects the stability of the tissue scaffolds. In this study, the biodegradable material polycaprolactone(PCL) was used to directly write electrospinning by using a self-designed melt electrospinning three-dimensional controllable molding equipment. The eff ects of nozzle temperature, lap time of hot and cold fibers, and ambient temperature on fiber bonding were investigated and characterized by a thermogravimetric analyzer(TGA). The results show that the degree of bonding between fibers increases first with the increase of nozzle temperature, and then decreases after slight fluctuations. The bonding degree reaches the maximum in the temperature range of 190-210℃. With the increase of the lap time between cold and hot fibers, the bonding degree of fibers decreases continuously. The increase of ambient temperature has a great influence on bonding eff ect between the fibers.
作者
雷文龙
张莉彦
李轶
杨卫民
李好义
陈明军
Lei Wenlong;Zhang Liyan;Li Yi;Yang Weimin;Li Haoyi;Chen Mingjun(College of Mechanical and Electrical Engineering,Beijing University of Chemical Technology,Beijing 100029,China;National Key Laboratory of Organic-Inorganic Composite Materials,Beijing University of Chemical Technology,Beijing 100029,China)
出处
《塑料科技》
CAS
北大核心
2018年第10期21-25,共5页
Plastics Science and Technology
基金
国家自然科学基金(51603009)
关键词
电纺直写
三维平台
聚己内酯
黏结
Electrospinning direct write
Three-dimensional platform
Polycaprolactone
Bonding