主动脉瓣钙化定量分析方法研究现状

Research progress of methods allowing quantitative analysis of aortic valve calcification

随着医疗水平及社会经济状况的发展,退行性瓣膜疾病在心脏瓣膜疾病发病所占的比例逐渐上升。钙化性主动脉瓣疾病(CAVD)是退行性瓣膜疾病最具代表性表现。研究表明主动脉瓣钙化(AVC)可显著提高心血管事件发生率,有效评估主动脉瓣钙化程度可以一定程度评估主动脉瓣疾病预后情况。目前主动脉瓣钙化定量分析方法报道较多但尚无统一标准,现就主动脉瓣钙化程度从组织病检、影像学两方面对主动脉钙化定量分析方法进行综合讨论。

With the development of social economy and medicine, degenerative heart valve disease has become the major part in heart valve disease. Calcific aortic valve disease （CAVD） is one of the most representative manifestations of degenerative valvular disease. Aortic valve calcification （AVC） has been found to be a strong predictor of major cardiovascular events, which makes it necessary to identify an effective way to evaluate the degree of AVC. Numerous methods of quantitative assessment of AVC have been reported. Here, we discuss these methods from the aspects of pathology and imageology.