Ⅱ型糖尿病牙周炎及牙周基础治疗对其影响的现状研究

Research on the present situation of interplay of type 2 diabetes mellitus, chronic periodontitis and non-surgical periodontal treatment

Ⅱ型糖尿病是引起慢性牙周炎的主要危险因素之一,慢性牙周炎增加了Ⅱ型糖尿病的患病风险,但至今为止糖尿病牙周炎的发病机制尚未明确。牙周基础治疗不仅可以改善牙周炎患者的牙周状况,而且在一定程度上改善了糖尿病牙周炎患者的血糖状况。随着分子生物学技术的不断发展,研究人员对糖尿病牙周炎疾病在微生物、免疫及炎症因子方面的研究不断深入,该文对糖尿病牙周炎的微生物指标,免疫、炎症因子指标,临床指标及牙周基础治疗对疾病的影响做一综述。

Type 2 diabetes mellitus is one of the major risk factors of chronic periodontitis, while chronic periodontitis increases the risk of type 2 diabetes mellitus. However, the pathogenesis of type 2 diabetes mellitus and chronic periodontitis has not been clarified so far. Non-surgical periodontal treatment can not only improve the condition of the periodontal tissues, but also ameliorate the blood glu- cose status of patients in some degree. With the development of molecular biology technology, studies on type 2 diabetes mellitus and chronic periodontitis from the perspectives of microorganisms, immunity, and inflammatory factors have been constantly deepened. In this paper, a review about the microbial indicators, immunity, inflammation indicators, clinical indicators of type 2 diabetes mellitus and chronic periodontitis was made. The effect of non-surgical periodontal treatment on illness was also reviewed carefully.