肝癌术后复发危险因素影响研究进展

Progression in influential factors of heatocellular carcinoma recurrence

目前肝癌患者术后5年复发率仍高达70％以上，是导致患者预后不良的重要因素。研究表明，肿瘤自身特征（如肿瘤大小、分化程度、血管浸润等）、手术相关因素（如手术切缘、入路，术中出血及输血）以及患者自身及肝移植相关因素（如肝病、供体年龄、受者乙肝病毒感染等）均可影响肝癌术后的复发率。我们通过复习文献，对肝癌术后复发的影响因素作一综述。

Primary liver cancer is one of the most malignant tumor in the worldwide. 5 years recurrence rate of patients in the early phase is exceeding 70%. Recurrence of HCC is one of the vital factors leading to adverse outcomes. Researchers found that characteristics of tumors, such as tumor size, differentiation and vascular invasion; operation aspect, such as surgical margin width, surgical approach, intraoperative bleeding and transfusion; patient-self and liver transplantation related factors, such as liver disease, donor＇s age, hepatitis B virus infection of recipient can affect the postoperative recurrence of hepatoeellular carcinoma. We summarized the influence factors of postoperative recurrence of HCC via literature review.