广场舞对超重绝经后女性循环骨钙素水平的影响及相关因素分析

The Effect of Square Dance on Circulating Osteocalcin Concentration of Overweight Postmenopausal Women

目的:研究绝经后女性循环骨钙素水平与能量代谢指标之间的相关性,探讨8周广场舞干预对超重绝经后女性循环骨钙素水平的影响并进行相关性分析。方法:67名符合研究条件的绝经后女性在自愿参加本研究的基础上填写调查问卷并签署知情同意书,按体重指数分成正常组、超重组和肥胖组后,从超重组中选取21名受试者进行为期8周的广场舞干预。实验开始前和结束后分别进行常规人体形态学指标测量以及与糖、脂代谢相关的生化指标的检测。血清骨钙素水平的检测采用电化学发光法。结果:全体绝经后女性受试者血清骨钙素水平与体重、体重指数(BMI)、心率、腰围、空腹血糖以及胰岛素抵抗指数负相关;其中,BMI正常者血清骨钙素水平与心率、腰围和胰岛素抵抗指数负相关,超重者骨钙素水平与年龄、甘油三酯、空腹血糖和胰岛素抵抗指数负相关,而肥胖者骨钙素水平只与总胆固醇负相关;超重绝经后女性运动后的血清骨钙素水平没有显著变化。结论:广场舞对超重绝经后女性循环骨钙素水平没有影响,但可以改变绝经后妇女的骨钙素水平和能量代谢之间的联系。

Objective To study the correlation between the osteocalcin level and energy metabolismof postmenopausal women,explore the effect of 8-week square dance intervention on the osteocalcin lev-el of overweight postmenopausal women and conduct the correlation analysis. Methods Sixty-seven post-menopausal women were selected and randomly divided into a normal group,an overweight group andan obese group according to their body mass index（BMI）. Twenty-one subjects were selected from theoverweight group for 8 weeks of square dance intervention. Morphological,glucose and lipid metabolicindicators were measured before and after the intervention. Serum osteocalcin levels were detected us-ing the electrochemiluminescence. Results The serum osteocalcin level of all postmenopausal womenwas negatively correlated with their body weight,BMI,heart rate,waist circumference,fasting glucose andinsulin resistance. The serum osteocalcin level of postmenopausal women with normal BMI was negative-ly correlated with the heart rate,waist circumference and insulin resistance index,while that of over-weight postmenopausal women was negatively associated with their age,triglycerides,fasting glucose andinsulin resistance index. However,that of obese postmenopausal women was only negatively correlatedwith the total cholesterol level. There was no significant change in the serum osteocalcin level of theobese postmenopausal women after exercise. Conclusion Square dancing has no effect on the circulat-ing osteocalcin level of overweight postmenopausal women,but can alter the relationship between the osteocalcin level and energy metabolism of postmenopausal women.